李飞,博士,博士生导师,研究员,深圳市高层次专业人才。2005年和2008年在四川大学分别获得工程力学学士和生物医学工程硕士学位;2013年于北京航空航天大学获得生物医学工程博士学位;2013年加入中国科学院深圳先进技术研究院。主要研究领域包括声镊技术及其生物医学应用、声学人工结构、可穿戴超声器件、超声造影成像技术、微泡非线性声学特性、超声力学效应等。主持国家自然科学基金面上、国自然青年基金、深圳基础研究重点等项目;参与国自然重点、国自然重大仪器、国家重点研发计划等项目。在Nature Communications, Physical Review Applied,Applied Physics Letters, IEEE Trans Ultrason Ferroelectr Freq Control,IEEE Transactions on Biomedical Engineering,Ultrasound in Medicine and Biology,Biomaterials,Research等期刊发表SCI论文30余篇。“声筛”相关研究被美国物理学会、美国物理联合会、美国化学学会列为“封面文章”、“亮点研究”、“编辑推荐”和“突破性研究”。授权10余项国家发明专利,1项美国发明专利,1项英国发明专利,转化3项。声镊理论及其操控效应的相关工作获得2019年度深圳市自然科学一等奖。

  1)Fei Han#, Hanfei Li#, Laixin Huang#, Xiaomeng Zhou, Rui Su, Huan Yu, Qiong Tian, Hang Zhao, Qingsong Li, Jing Sun, Mei Yu, Xinping Deng, Guanglin Li, Huaiyu Ye*, Fei Li*, Guoqi Zhang*, Zhiyuan Liu*, Hybrid microstructure-based stretchable biosensors for multi-physiological signal sensing, eScience, 2024. (IF: 42.9)

  2)Changcan Li#, Gang Xu#, Yinhan Wang#, Laixin Huang, Feiyan Cai, Long Meng, Bao Jin, Zhuoran Jiang, Hang Sun, Haitao Zhao, Xin Lu, Xingting Sang, Pengyu Huang, Fei Li*, Huayu Yang*, Yilei Mao*, Hairong Zheng*, Acoustic-Holography-Patterned Primary Hepatocytes Possess Liver Functions, Biomaterials, 2024, 311, 122691. (IF: 12.8)

  3)Zong-Lin Li#, Kun Chen#, Fei Li#(co-first author), Zhi-Jun Shi, Qi-Li Sun, Peng-Qi Li, Yu-Gui Peng, Lai-Xin Huang, Guang Yang*, Hairong Zheng*, and Xue-Feng Zhu*, Decorated bacteria-cellulose ultrasonic metasurface, Nature Communications, 2023,14:5319. (IF: 14.7)

  4)Hu X#, Li F# (co-first author), Zeng J#, Zhou Z, Wang Z, Chen J, Cao D, Hong Y, Huang L, Chen Y, Xu J*, Dong F*, Yu R*, Zheng H*, Non-invasive Low-frequency Pulsed Focused Ultrasound Therapy for Rheumatoid Arthritis in Mice, Research, 2022, Article ID: 0013.

  5)Huang L#, Li F# (co-first author), Cai F, Meng L, Zhou W, Kong D, Zheng H*, Phononic crystal-induced standing Lamb wave for the translation of subwavelength microparticles, Applied Physics Letters, 2022, 121, 023505.

  6)Lu H#, Xu G#, Wang Y#, Yang H, Li D, Huang L, Su M, Li C, Qiu W, Mao Y*, Yu W*, Li F*, Correlation Between Portal Vein Pressure and Subharmonic Scattering Signals From SonoVue Microbubbles in Canines, Ultrasound in Medicine & Biology, 2023, 49(1):203-211.

  7)Xu G, Lu H, Yang H, Li D, Liu R, Su M, Li C, Lv T, Du S, Yang J, Qiu W, Mao Y*, and Li F*, Subharmonic Scattering of SonoVue Microbubbles within 10–40 mmHg Overpressures in Vitro, IEEE Trans Ultrason Ferroelectr Freq Control, 2021, 68(12):3583-3591.

  8)Xu G#, Wang Y#, Lu H#, Li C, Huang L, Su M, Yang H, Li D, Qiu W, Sun M, Yang J, Mao Y*, Li F*, Portal vein pressure estimation and portal hypertension discrimination based on subharmonic scattering of ultrasound contrast agent microbubbles, IEEE Transactions on Biomedical Engineering, 2024, 71(1):150-159.

  9)Xu G, Li F*, Mao Y*, Portal pressure monitoring—state-of-the-art and future perspective, Annals of Translational Medicine, 2019, 7(20):583. (Review Article)

  10)Laixin Huang, Shi-Chun Bao, Feiyan Cai, Long Meng, Wei Zhou, Juan Zhou, Deqing Kong, Fei Li*, Hairong Zheng*, Acoustic rotation of multiple subwavelength cylinders for three-dimensional topography reconstruction, Journal of Applied Physics, 2023, 134, 204501.

  11)Li F, Cai F*, Zhang L, Liu Z, Li F, Meng L, Wu J, Li J, Zhang X and Zheng H*, Phononic-Crystal-Enabled Dynamic Manipulation of Microparticles and Cells in an Acoustofluidic Channel, Physical Review Applied, 2020,13: 044077. (Highlights, Featured in Physics, Editors’ Suggestion)

  12)Li F#, Cai F#, Liu Z, Meng L, Qian M, Wang C, Cheng Q, Qian M, Liu X, Wu J, Li J, and Zheng H*, Phononic Crystal Based Acoustic Sieve for Tunable Manipulations of Particles by Highly Localized Radiation Force, Physical Review Applied, 2014,1: 051001. (Highlights, Featured in Physics, Editors’ Suggestion)

  13)Li F#, Xia X#, Deng Z#, Lei J, Shen Y, Lin Q, Zhou W, Meng L, Wu J, Cai F*, Zheng H*, Ultrafast Rayleigh-like streaming in a sub-wavelength slit between two phononic crystal plates, Journal of Applied Physics, 2019, 125, 134903.

  14)Li F#, Yan F#, Chen Z#, Lei J, Yu J, Chen M, Zhou W, Meng L, Niu L, Wu J, Li J, Cai F*, and Zheng H*, Phononic Crystal-enhanced Near-boundary Streaming for Sonoporation, Applied Physics Letters, 2018a, 113, 083701. (Front Cover, Featured, Breaking Research)

  15)Li F#, Xiao Y#, Lei J, Xia X, Zhou W, Meng L, Niu L, Wu J, Li J, Cai F*, and Zheng H*, Rapid acoustophoretic motion of microparticles manipulated by phononic crystals, Applied Physics Letters, 2018b, 113, 173503.

  16)Li F#, Wang Y#, Mo X, Deng Z, Yan F*, Acoustic Characteristics of Biosynthetic Bubbles for Ultrasound Contrast Imaging, Langmuir, 2019, 35(31): 10213-10222. (Cover)

  1)中科院先导B专项课题,XDB0930000,面阵列声全息辐照与投射技术研究,2024/07-2029/06,678万元,在研,主持

  2)国家重点研发计划,2024YFC2418000,面向心房颤动防治的低强度聚焦超声外周神经可视化调控技术研究及样机研发,2024/12-2027/11,250万元,在研,参与

  3)国家自然科学基金面上项目,12074402,在体检测循环肿瘤细胞的血管内声操控方法研究,2021/01-2024/12,63万元,在研,主持

  4)国家自然科学基金面上项目,11774369,人工结构声场定量调控声流剪切力诱发声孔效应的研究,2018/01-2021/12,65万元,已结题,主持

  5)国家自然科学基金重大仪器项目,81927808,基于超声的脑损伤连续动态成像和监测仪器研制,2020/01-2024/12,655万元,在研,参与 (合作单位负责人)

  6)深圳市基础研究重点项目,JCYJ20200109114825064,适形可穿戴式智能心血管超声终端关键技术研究,2020/11-2023/11,250万元,主持

  7)深圳市国际合作项目,GJHZ20210705141404012,基于声镊捕获循环肿瘤细胞的关键技术研究,2022/07-2024/07,50万元,主持

  8)国家重点研发计划子课题,2020YFA0908801,超声造影剂的生物合成与调控,挖掘超声成像元件及模块,2020/11-2025/10,444万元,在研,参与

  9)国家自然科学基金重点项目,11534013,可调制超声场诱发细胞生物效应的研究,2016/01-2020/12,352.8万元,已结题,参与

  10)国家自然科学基金青年基金,11404363,基于人工结构声场可定量调控声流效应的微纳颗粒操控研究,2015/01-2017/12,30万元,已结题,主持

  11)第56批中国博士后科学基金面上资助 一等,2014M560682,2014/09-2015/09,基于人工结构声场声流效应的微纳颗粒操控研究,8万元,已结题,主持

  1)李飞,张鹏飞,蔡飞燕,郑海荣,黄继卿,周伟,肖杨,邱维宝,李永川,苏敏,一种声镊装置,CN201711398091.9,2021-03-23

  2)郑海荣,李飞,蔡飞燕,孟龙,王辰,张成祥,邱维宝,李永川,严飞,牛丽丽,耿刘峰,徐超伟, Microfluidic system and method of controlling particles based on artificially structured acoustic field, US15/742491, 2015-10-10(美国专利)

  3)蔡飞燕,李飞,王辰,邱维宝,孟龙,王丛知,肖杨,郑海荣,一种基于时间反转技术操控微粒的系统与方法,CN201710214161.4,2017-04-01

  4)郑海荣,李飞,蔡飞燕,孟龙,王辰,张成祥,邱维宝,李永川,严飞,牛丽丽,耿刘峰,徐超伟,基于人工结构声场的微流体系统及操控微粒的方法,CN201510655483.3,2015-10-10

  5)肖杨,李飞,王丛知,邓志婷,郑海荣,不可逆声穿孔设备、装置及计算机可读存储介质,CN202011453218.4,2022-07-19

  6)郑海荣,李飞,蔡飞燕,孟龙,肖杨,严飞,微流体系统及其操作方法,CN201811572013.0,2022-02-22

  7)郑海荣,李飞,蔡飞燕,夏向向,肖杨,严飞,一种微流体装置及其制造和使用方法,CN201811532600.7,2022-01-28

  8)郑海荣,李飞,蔡飞燕,许迪,夏向向,孟龙,肖杨,邱维宝,李永川,苏敏,黄继卿,一种声驱动的流式细胞检测装置,CN201711396348.7,2021-08-24

  9)郑海荣,李飞,黄来鑫,孟龙,造影剂微泡声学特性测量方法、装置、设备及存储介质,CN202211474013.3,2022-11-23

  10)郑海荣,李飞,王云,黄来鑫,孟龙,微泡背向散射系数测量方法、装置、设备及存储介质,CN202211471365.3,2022-11-23

  11)郑海荣,李飞,徐岗,卢慧敏,王云,黄来鑫,肖杨,基于超声造影成像技术的信号处理系统、方法及终端设备,CN202110542505.0,2021-05-18

  12)郑海荣,李飞,黄来鑫,苏敏,周娟,一种基于单阵元超声脉冲回波的血压测量系统及方法,CN202111406926.7,2021-11-24

  13)郑海荣,李飞,王珊珊,蔡飞燕,孟龙,苏敏,黄继卿,生物3D打印系统与方法,CN201910313928.8,2019-04-18