中国科学院深圳先进技术研究院高级工程师,深圳市后备人才。2008年7月至今在中国科学院深圳先进技术研究院从事科研工作,研究领域为分子影像探针、肿瘤诊断和治疗。擅长肿瘤光学治疗、化疗和免疫治疗以及多种成像探针的制备等。主持国家自然科学基金3项目,广东省和深圳市项目4项。已发表60余篇SCI 收录学术论文,其中第一作者论文20 余篇,总引用次数6600 余次,H-index 指数为43。包括Advanced Materials, ACS nano 等知名学术期刊。申请中国发明专利六十余项,成功转让15 项。
1.Dehong Hu#; Menglei Zha#; Hairong Zheng; Duyang Gao*; Zonghai Sheng*. Recent Advances in Indocyanine Green-Based Probes for NIR-II Fluorescence Imaging and Therapy. Research, 2025.
2.Yu Liu#, Dehong Hu#, Duyang Gao*, Ping Gong, Hairong Zheng, Minjie Sun*, Zonghai Sheng*, Engineered apoptotic bodies hitchhiking across the blood-brain barrier achieved a combined photothermal-chemotherapeutic effect against glioma, Theranostics, 2023, 13, 2966-2978
3.Simin Liang#; Dehong Hu#; Guofeng Li; Duyang Gao; Fei Li; Hairong Zheng; Min Pan; Zonghai Sheng. NIR-II fluorescence visualization of ultrasound-induced blood–brain barrier opening for enhanced photothermal therapy against glioblastoma using indocyanine green microbubbles. Science bulletin, 2022, 67(22): 2316-2326.
4.Zichao Luo#; Dehong Hu#; Duyang Gao; Zhigao Yi; Hairong Zheng; Zonghai Sheng; Xiaogang Liu. High‐Specificity In Vivo Tumor Imaging Using Bioorthogonal NIR‐IIb Nanoparticles. Advanced Materials, 2021, 33(49): 2102950.
5.Xinping Luo#; Dehong Hu#; Duyang Gao; Yuenan Wang; Xinhua Chen; Xin Liu; Hairong Zheng; Minjie Sun; Zonghai Sheng. Metabolizable near-infrared-II nanoprobes for dynamic imaging of deep-seated tumor-associated macrophages in pancreatic cancer. ACS nano, 2021, 15(6): 10010-10024.
6.Yaxi Li#; Dehong Hu#; Zonghai Sheng; Tianliang Min; Menglei Zha; Jen-Shyang Ni; Hairong Zheng; Kai Li. Self-assembled AIEgen nanoparticles for multiscale NIR-II vascular imaging. Biomaterials, 2021, 264: 120365.
7.Hu Dehong, Sheng Zonghai, Zhu Mingting, Wang Xiaobing, Yan Fei, Liu Chengbo, Song Liang, Qian Ming, Liu Xin, Zheng Hairong, Förster Resonance Energy Transfer-Based Dual-Modal Theranostic Nanoprobe for In Situ Visualization of Cancer Photothermal Therapy, Theranostics, 2018, 8(2): 410-422
8.Dehong Hu, Zonghai Sheng, Guanhui Gao, Fungming Siu, Chengbo Liu, Qian Wan, Ping Gong, Hairong Zheng, Yifan Ma, Lintao Cai, Activatable albumin-photosensitizer nanoassemblies for triple-modal imaging and thermal-modulated photodynamic therapy of cancer. Biomaterials, 2016, 93: 10-19.
9.Bo Hou #; Luying Yi #; Dehong, Hu; Zichao Luo; Duyang Gao; Chao Li; Bowen Xing; Jiong-Wei Wang; Chuen Neng Lee; Rong Zhang; Zonghai Sheng*; Bin Zhou*; Xiaogang Liu*. A swallowable X-ray dosimeter for the real-time monitoring of radiotherapy, Nature Biomedical Engineering, 2023, 7, 1242–1251.
1.国家自然科学基金委员会,面上项目,超声联合NIRII金簇纳米药物可视化治疗胶质瘤的方法与机制研究,2022.01至2025.12,55万元,在研,主持
2.国家自然科学基金委员会,面上项目,近红外二区荧光/光声双模态分子成像探针用于脑胶质瘤边界精准识别研究,2018.01至2021.12,55万元,结题,主持
3.国家自然科学基金委员会, 青年科学基金项目, 白蛋白-吲菁绿纳米粒子用于成像引导的肿瘤靶向光热治疗研究,2015.01-2017.12,23万元, 结题, 主持
4.广东省科技厅,广东省面上项目,脑胶质瘤浸润边界精准识别的凋亡小体仿生磁光双模纳米探针研究,2022.01至2024.12,10万元,结题,主持
5.深圳市科技创新委员会,基础研究(自由探索),双模态分子成像探针用于脑胶质瘤边界精准识别研究,2018.03至2020.03,30万元,结题,主持
6.深圳市科技创新委员会,基础研究(面上项目),近红外二区AIE探针动态可视化超声开放血脑屏障的实验研究,2020.02至2023.01,30万元,结题,主持
7.深圳市科技创新委员会,基础研究(自由探索),智能化纳米粒子用于脑胶质瘤的成像与光学治疗,2016.07至2018.07,30万元,结题,主持
(1) 盛宗海,胡德红,郑海荣,刘新,一种二硬脂酰磷脂酰乙醇胺的制备方法,CN202011421108.X,20201210,发明
(2) 郑海荣,胡德红,盛宗海,刘新,一种肿瘤诊疗药物及其制备方法和应用,CN202011449514.7,2020-12-11,发明
(3) 郑海荣,胡德红,罗新平,盛宗海,马腾,高笃阳,一种巨噬细胞示踪荧光探针的制备方法及应用,CN201911279822.7,20191213 ,发明
(4) 郑海荣,胡德红,盛宗海,刘新,多聚体白蛋白纳米球及其制备方法和应用、载药多聚体白蛋白纳米球及其制备方法和应用, PCT/CN2019/123329
(5) 郑海荣,胡德红,盛宗海,刘新,组织透明化试剂及其制备方法和应用,CN202011287244.4,20201117,发明
(6) 郑海荣,胡德红,盛宗海,刘新,纳米颗粒及其制备方法和应用、药剂,ZL201811555017.8,20181218,发明
(7) 郑海荣,胡德红,盛宗海,一种可注射的肿瘤靶向性热敏前药及其制备方法与应用,中国,CN201610958535.9,2016-10-27,发明
(8) 郑海荣,胡德红,盛宗海,一种肿瘤靶向性热敏前药及其制备方法与应用,CN201610968541.2,2016-10-27,发明
(9) 盛宗海,郑海荣,胡德红,刘新,杀菌剂及其制备方法和应用,CN202011267146.4,20201113,发明
(10) 马腾,王丛知,胡德红,盛宗海,肖杨,郑海荣,多模态胰胆管成像系统,2018127,PCT/CN2018/119822
